Short term corticosteroid use side effects

Certain drugs such as troleandomycin (TAO), erythromycin ( Ery-Tab , EryPed 200), and clarithromycin ( Biaxin ) and ketoconazole ( Nizoral ) can reduce the ability of the liver to metabolize (breakdown) corticosteroids and this may lead to an increase in the levels and side effects of corticosteroids in the body. On the other hand, phenobarbital, ephedrine , phenytoin ( Dilantin ), and rifampin ( Rifadin , Rimactane ) may reduce the blood levels of corticosteroids by increasing the breakdown of corticosteroids by the liver. This may necessitate an increase of corticosteroid dose when they are used in combination with these drugs.

For this 2015 update we searched the Cochrane Central Register of Controlled Trials (CENTRAL 2015, Issue 7), which includes the Cochrane Acute Respiratory Infections Group's Specialised Register; MEDLINE (January 1966 to August 2015) and EMBASE (January 1974 to August 2015). We also searched trials registries, however we did not identify any new relevant completed or ongoing trials for inclusion. We combined the MEDLINE search with the Cochrane search strategy for identifying randomised controlled trials ( RCTs ). We adapted the search terms when searching EMBASE .

Patients’ inhaler technique can be improved by brief education, including a physical demonstration, from a health professional or other person trained in correct technique. 68 The best way to train patients to use their inhalers correctly is one-to-one training by a healthcare professional (. nurse, pharmacist, GP, specialist), that involves both verbal instruction and physical demonstration. 74 ,   62 ,   75 ,   76  Patients do not learn to use their inhalers properly just by reading the manufacturer's leaflet. 75 An effective method is to assess the individual's technique by comparing with a checklist specific to the type of inhaler, and then, after training in correct technique, to provide written instructions about errors (. a sticker attached to the device). 60 ,   73

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  • Citation tools Download this article to citation manager Waljee Akbar K , Rogers Mary A M , Lin Paul , Singal Amit G , Stein Joshua D , Marks Rory M et al. Short term use of oral corticosteroids and related harms among adults in the United States: population based cohort study BMJ 2017; 357 :j1415
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    Short term corticosteroid use side effects

    short term corticosteroid use side effects

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  • Citation tools Download this article to citation manager Waljee Akbar K , Rogers Mary A M , Lin Paul , Singal Amit G , Stein Joshua D , Marks Rory M et al. Short term use of oral corticosteroids and related harms among adults in the United States: population based cohort study BMJ 2017; 357 :j1415
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