Inhaled corticosteroid potency comparison

In the initiation population (n = 797 in each cohort), children prescribed small-particle ICS versus standard size-particle ICS experienced greater odds of asthma control (adjusted odds ratio, ; 95% CI, -) and lower severe exacerbation rate (adjusted rate ratio, ; 95% CI, -). Step-up outcomes (n = 206 in each cohort) were also significantly better for small-particle ICS, with asthma control adjusted odds ratio of (95% CI, -) and exacerbations adjusted rate ratio of (95% CI, -). The number needed to treat with small-particle ICS to achieve 1 additional child with asthma control was 17 (95% CI, 9-107) for the initiation population and 5 (95% CI, 3-78) for the step-up population. Outcomes were not significantly different for stepped-up small-particle ICS dose versus ICS/LABA combination (n = 185 in each cohort).

Inhaled corticosteroid potency comparison

inhaled corticosteroid potency comparison

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