Effectiveness of second corticosteroid injections for carpal tunnel syndrome

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Among older adults, annual influenza vaccination was recommended based on the high burden of influenza-related disease and demonstrated vaccine efficacy among younger adults. One RCT of adults aged 60 years and older relied on serology for confirmation of influenza and reported a vaccine efficacy of 58% (95% confidence interval (CI): 26-77) [2] . However, it is unknown if infections were missed by serology among the study participants that were vaccinated (and if the vaccine efficacy estimate is biased upwards – see previous description of how bias can occur in VE studies that test for influenza using serology). A meta-analysis of observational studies that used the test-negative design provided VE estimates for adults aged >60 years against RT-PCR confirmed influenza infection. This meta-analysis reported significant vaccine effectiveness of 52% (95% CI: 41-61) during seasons when the vaccine and circulating viruses were well-matched [3] . During seasons when the circulating viruses were antigenically drifted (not well matched), reported VE was 36% (95% CI: 22-48) 3 .

An example: we read that peridontal disease is associated with heart attacks. The message given to the public is to floss your teeth. It is certainly a cheap therapy (and there is no doubt it is good for your dental health). But is this statistically significant correlation an indication of causation or an indication that people who take care of their teeth also eat a healthy diet? In terms of benefit/cost ratio this must rank extremely high, but even if the benefit is real (rather than a consequence of the flossing population having other healthy habits), it should not exclude more expensive therapies.

The goal of the Fundraising Effectiveness Project (FEP) is to help nonprofit organizations increase giving at a faster pace. FEP pursues this goal by providing nonprofits with tools for tracking and evaluating their annual growth in giving. Growth in giving is the net of gains in giving minus losses in giving. Nonprofits raise more money by investing more money in growth-oriented fundraising strategies that both increase gains and reduce losses. The FEP is focused on “effectiveness” (maximizing growth in giving) rather than “efficiency” (minimizing costs). FEP conducts an annual survey, provides useful growth in giving performance measurement tools and publishes gain(loss) statistics in a yearly report through a partnership between AFP, The Urban Institute and participating donor software firms. The FEP resources support growth-oriented fundraising programs.

The specific point system that TES uses to rate teachers as Proficient and Distinguished is somewhat arbitrary. For a better sense of the magnitude of these estimates, consider a student who begins the year at the 50th percentile and is assigned to a top-quartile teacher as measured by the Overall Classroom Practices score; by the end of the school year, that student, on average, will score about three percentile points higher in reading and about two points higher in math than a peer who began the year at the same achievement level but was assigned to a bottom-quartile teacher.

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Effectiveness of second corticosteroid injections for carpal tunnel syndrome

effectiveness of second corticosteroid injections for carpal tunnel syndrome

The goal of the Fundraising Effectiveness Project (FEP) is to help nonprofit organizations increase giving at a faster pace. FEP pursues this goal by providing nonprofits with tools for tracking and evaluating their annual growth in giving. Growth in giving is the net of gains in giving minus losses in giving. Nonprofits raise more money by investing more money in growth-oriented fundraising strategies that both increase gains and reduce losses. The FEP is focused on “effectiveness” (maximizing growth in giving) rather than “efficiency” (minimizing costs). FEP conducts an annual survey, provides useful growth in giving performance measurement tools and publishes gain(loss) statistics in a yearly report through a partnership between AFP, The Urban Institute and participating donor software firms. The FEP resources support growth-oriented fundraising programs.

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